⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997780 | 0.77 | — | — | |
| Chloroform SCHEMBL1674189 | 0.75 | PIK3CD (0.33) | — | |
| SCHEMBL6946486 | 0.74 | — | — | |
| SCHEMBL5561419 | 0.74 | — | — | |
| SCHEMBL14685168 | 0.72 | — | — | |
| Chloroform SCHEMBL11153586 | 0.72 | PIK3CD (0.32) | — | |
| SCHEMBL4356647 | 0.70 | PIK3CD (0.30) | — | |
| SCHEMBL29689415 | 0.69 | THRB (0.39) | — | |
| SCHEMBL3930184 | 0.69 | — | — | |
| SCHEMBL20602876 | 0.69 | CA2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294066-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009134750-A1 | BENZOIMIDAZOLES AS PROLYL HYDROXYLASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | WO | disclosed |