Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681294 | 0.91 | KDM4E (0.47) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL1267349 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL10498542 | 0.84 | LMNA (0.70) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL6663539 | 0.84 | — | — | |
| SCHEMBL3339822 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL18228600 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL2168776 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL1928132 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| SCHEMBL2951425 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1LMNAMAPTUSP2 | |
| Ammonia Solution, Strong SCHEMBL28080150 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1LMNAMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694659-B1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2008-08-27 | — | — | EP | disclosed |