Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13829276 | 0.88 | HDAC4 (0.40) | IFNAR1HSD17B1HSD17B2ALDH1A1LMNA | |
| SCHEMBL13829340 | 0.88 | GSTP1 (0.39) | IFNAR1HSD17B1HSD17B2ALDH1A1LMNA | |
| SCHEMBL12887109 | 0.88 | CYP11B1 (0.40) | MAPK8MAPK9MAPK10SIRT2SIRT1 | |
| SCHEMBL14100986 | 0.83 | IFNAR1 (0.41) | IFNAR1ALDH1A1LMNANPY1RMAPK1 | |
| SCHEMBL14100989 | 0.82 | TUBB4A (0.42) | HSD17B1HSD17B2ALDH1A1LMNAGSTP1 | |
| SCHEMBL13829192 | 0.82 | ESR1 (0.33) | IFNAR1HSD17B1HSD17B2ALDH1A1LMNA | |
| SCHEMBL29350362 | 0.79 | ESR1 (0.52) | HSD17B1HSD17B2ALDH1A1GSTP1ESR1 | |
| SCHEMBL36279 | 0.79 | ESR1 (0.52) | HSD17B1HSD17B2ALDH1A1GSTP1ESR1 | |
| SCHEMBL12887165 | 0.79 | MAPK9 (0.39) | ALDH1A1LMNAMAPK1MAPK8MAPK9 | |
| SCHEMBL2379728 | 0.79 | ESR1 (0.52) | HSD17B1HSD17B2ALDH1A1GSTP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | OR10J3, DDT, EML4 | IFNAR1 4692/4885HSD17B1 3990/4885HSD17B2 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.