SCHEMBL14101018

SCHEMBL14101018

c1ccc(Oc2ccc3c(c2)c(-c2ccccc2)c(-c2ccccc2)c2cc(-c4ccccc4)ccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.44
GSTP1 P09211 1/20 0.44
FFAR1 O14842 1/20 0.44
LTA4H P09960 3/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
BLM P54132 1/20 0.40
MCL1 Q07820 1/20 0.40
ICMT O60725 1/20 0.40
ACHE P22303 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAOB P27338 1/20 0.39
SCN9A Q15858 1/20 0.39
CHEK1 O14757 1/20 0.38
FGFR1 P11362 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14363729 0.88 GSTP1 (0.46) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL13158754 0.86 GSTP1 (0.43) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL14101007 0.85 FFAR4 (0.43) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL6762026 0.84 LTA4H (0.46) GSTP1LTA4HTSHRPOLBCYP1A2
SCHEMBL19891793 0.79 FFAR4 (0.61) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL10453614 0.79 FFAR4 (0.61) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL13158745 0.78 KDM4E (0.41) FFAR4GSTP1FFAR1TSHRPOLB
SCHEMBL11814889 0.77 FFAR4 (0.59) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL11820542 0.77 FFAR4 (0.55) FFAR4GSTP1FFAR1LTA4HTSHR
SCHEMBL19845795 0.77 FFAR4 (0.55) FFAR4GSTP1FFAR1LTA4HTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080166593-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-07-10 US disclosed
US-20080166593-A1 Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166593-A1 Organic Electroluminescent Devices OR10J3, DDT, EML4 FFAR4 4628/4885GSTP1 684/4885FFAR1 4809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.