Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4945156 | 1.00 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL4944709 | 1.00 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL14100772 | 0.93 | CCR2 (0.70) | CCR2 | |
| SCHEMBL14100895 | 0.92 | CCR2 (0.69) | CCR2 | |
| SCHEMBL14100898 | 0.92 | CCR2 (0.69) | CCR2 | |
| SCHEMBL14100791 | 0.90 | CCR2 (0.78) | CCR2CCR5 | |
| SCHEMBL14100769 | 0.90 | CCR2 (0.78) | CCR2CCR5 | |
| SCHEMBL14101175 | 0.89 | CCR2 (0.73) | CCR2 | |
| SCHEMBL14101168 | 0.89 | CCR2 (0.76) | CCR2 | |
| SCHEMBL14100915 | 0.88 | CCR2 (0.64) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501803-B1 | TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7166614-B2 | Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7166614-B2 | Tetrahydropyranyl cyclopentyl tetrahydroisoquinoline modulators of chemokine receptor activity | MERCK & CO., INC. (US) | 2007-01-23 | — | — | US | disclosed |