Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101024 | 1.00 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL4944709 | 1.00 | CCR2 (0.69) | CCR2CCR5 | |
| SCHEMBL14100772 | 0.93 | CCR2 (0.70) | CCR2 | |
| SCHEMBL14100895 | 0.92 | CCR2 (0.69) | CCR2 | |
| SCHEMBL14100898 | 0.92 | CCR2 (0.69) | CCR2 | |
| SCHEMBL14100791 | 0.90 | CCR2 (0.78) | CCR2CCR5 | |
| SCHEMBL14100769 | 0.90 | CCR2 (0.78) | CCR2CCR5 | |
| SCHEMBL14101175 | 0.89 | CCR2 (0.73) | CCR2 | |
| SCHEMBL14101168 | 0.89 | CCR2 (0.76) | CCR2 | |
| SCHEMBL14100915 | 0.88 | CCR2 (0.64) | CCR2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194548-A1 | Drug Combination Therapy and Pharmaceutical Compositions for Treating Inflammatory Disorders | MERCK SHARP & DOHME CORP. | 2008-08-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194548-A1 | Drug Combination Therapy and Pharmaceutical Compositions for Treating Inflammatory Disorders | CCR2, CCR1, CCR5 | CCR2 1/4885CCR5 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.