Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646596 | 0.89 | KMT2A (0.34) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4646835 | 0.86 | KDM4E (0.40) | KMT2AMEN1GAAMAPTCHRNA7 | |
| SCHEMBL4646829 | 0.86 | KDM4E (0.40) | KMT2AMEN1GAAMAPTCHRNA7 | |
| SCHEMBL8171243 | 0.81 | NPC1 (0.55) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4647112 | 0.81 | NPC1 (0.55) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4648906 | 0.75 | KMT2A (0.39) | KMT2AMEN1GAAKDM4E | |
| SCHEMBL4648903 | 0.75 | KMT2A (0.39) | KMT2AMEN1GAAKDM4E | |
| SCHEMBL4648052 | 0.72 | PTPRC (0.40) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL4648045 | 0.72 | PTPRC (0.40) | KMT2AMEN1NPC1RAB9AGAA | |
| Naftazone SCHEMBL1697156 | 0.72 | MEN1 (0.44) | KMT2AMEN1GAARAD52MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |