Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648052 | 1.00 | PTPRC (0.40) | PTPRCSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL4648727 | 0.80 | KMT2A (0.39) | PTPRCMEN1KMT2AKDM4EGAA | |
| SCHEMBL4648731 | 0.80 | KMT2A (0.39) | PTPRCMEN1KMT2AKDM4EGAA | |
| Naftazone SCHEMBL1697156 | 0.76 | MEN1 (0.44) | PTPRCSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL14101161 | 0.72 | KMT2A (0.36) | MAPTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL4646835 | 0.72 | KDM4E (0.40) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL4646829 | 0.72 | KDM4E (0.40) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL4648906 | 0.72 | KMT2A (0.39) | PTPRCMEN1KMT2AKDM4EGAA | |
| SCHEMBL4648903 | 0.72 | KMT2A (0.39) | PTPRCMEN1KMT2AKDM4EGAA | |
| SCHEMBL4648976 | 0.72 | PSMD14 (0.39) | SMN1; SMN2MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |