Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.44 |
| ▸ | INSR | P06213 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171243 | 1.00 | NPC1 (0.55) | NPC1GAARAB9AMEN1NR2F2 | |
| SCHEMBL14101161 | 0.81 | KMT2A (0.36) | NPC1GAARAB9AMEN1NR2F2 | |
| SCHEMBL4646829 | 0.78 | KDM4E (0.40) | GAAMEN1KMT2AADORA2AADORA1 | |
| SCHEMBL8571844 | 0.72 | KDM4E (0.62) | NPC1GAARAB9AMEN1NR2F2 | |
| SCHEMBL5604414 | 0.72 | KDM4E (0.62) | NPC1GAARAB9AMEN1NR2F2 | |
| SCHEMBL30821234 | 0.72 | HRH3 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL4648976 | 0.72 | PSMD14 (0.39) | GAAMEN1KMT2AADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL11606453 | 0.71 | KDM4E (0.60) | NPC1GAARAB9AMEN1NR2F2 | |
| Hydrochloric Acid SCHEMBL11602807 | 0.71 | KDM4E (0.60) | NPC1GAARAB9AMEN1NR2F2 | |
| SCHEMBL17456926 | 0.71 | KMT2A (1.00) | NPC1GAARAB9AMEN1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |