Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNN4 | O15554 | 9/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398996 | 0.84 | MAPT (0.50) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL14101147 | 0.84 | MAPT (0.50) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL9211554 | 0.75 | MAPT (0.54) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL3936932 | 0.74 | MAPT (0.58) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL11842568 | 0.74 | CYP1A2 (0.70) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL4245525 | 0.73 | MAPT (0.56) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL4556174 | 0.73 | MAPT (0.56) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL2465581 | 0.73 | MAPT (0.56) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL17968493 | 0.73 | MAPT (0.56) | MAPTKMT2AKCNN4CYP1A2HTT | |
| SCHEMBL2705804 | 0.72 | MAPT (0.46) | MAPTKMT2AKCNN4CYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |