SCHEMBL4556174

SCHEMBL4556174

NC(=O)C(Cl)(Cl)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
KMT2A Q03164 1/20 0.56
CYP1A2 P05177 2/20 0.54
KCNN4 O15554 10/20 0.48
TSHR P16473 2/20 0.46
HTT P42858 1/20 0.46
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
KIF11 P52732 3/20 0.41
CYP2D6 P10635 1/20 0.41
KCNE1 P15382 1/20 0.41
KCNQ1 P51787 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11842568 0.83 CYP1A2 (0.70) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL7987418 0.80 CYP1A2 (0.58) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL2547243 0.80 CYP1A2 (0.65) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL9211554 0.79 MAPT (0.54) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL7593594 0.79 MAPT (0.54) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL6961047 0.78 CYP1A2 (0.56) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL3936932 0.78 MAPT (0.58) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL3086830 0.78 CYP1A2 (0.56) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL8818467 0.78 CYP1A2 (0.56) MAPTKMT2ACYP1A2KCNN4TSHR
SCHEMBL9518780 0.77 CYP1A2 (0.56) MAPTKMT2ACYP1A2KCNN4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775535-A Pure cation system photosensitive resin composition and preparation method thereof 上海信斯帝克新材料有限公司 2025-04-08 CN claimed
US-4801706-A ANTIARRHYTHMIA HYPOTENSIVE AMERICAN HOME PRODUCTS CORPORATION (US) 1989-01-31 US claimed
EP-0046859-B1 PROCESS FOR THE PREPARATION OF 1-BROMO-3,5-DICHLOROBENZENE BASF Aktiengesellschaft (DE) 1983-07-06 EP claimed
EP-0046859-A1 Process for the preparation of 1-bromo-3,5-dichlorobenzene BASF Aktiengesellschaft (DE) 1982-03-10 EP claimed
CN-119775535-A Pure cation system photosensitive resin composition and preparation method thereof 上海信斯帝克新材料有限公司 2025-04-08 CN disclosed
CN-105859692-B Thioether compound containing pyrimidine, thiadiazole ring and amide structure and application thereof 浙江工业大学 2018-02-27 CN disclosed
CN-105859692-A Thioether compound containing pyrimidine, thiadiazole ring and amide structure and application thereof 浙江工业大学 2016-08-17 CN disclosed
US-20090298781-A1 COMPOUNDS FOR THE INHIBITION OF APOPTOSIS CONSEJO SUPERIOR DE (ES) 2009-12-03 US disclosed
US-7417027-B2 Linear and cyclic melanocortin receptor-specific peptides PALATIN TECHNOLOGIES, INC. (US) 2008-08-26 US disclosed
EP-1319642-B1 Method of Preparing a Halogenated Compound OTSUKA KAGAKU KK (JP) 2008-03-26 EP disclosed
EP-1132391-B1 PROCESS FOR THE PREPARATION OF 3-SULFONYLOXY-3-CEPHEM COMPOUNDS OTSUKA KAGAKU KK (JP) 2006-11-15 EP disclosed
EP-1447406-B1 3-Cephem derivative crystal OTSUKA KAGAKU KK (JP) 2006-08-09 EP disclosed
EP-0445821-A1 Process for preparing a 3-formylcephem derivative OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1991-09-11 EP disclosed
EP-0444708-A2 Process for preparation of beta-lactam derivatives OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1991-09-04 EP disclosed
US-4801706-A ANTIARRHYTHMIA HYPOTENSIVE AMERICAN HOME PRODUCTS CORPORATION (US) 1989-01-31 US disclosed
US-4801706-A ANTIARRHYTHMIA HYPOTENSIVE AMERICAN HOME PRODUCTS CORPORATION (US) 1989-01-31 US disclosed
EP-0046859-B1 PROCESS FOR THE PREPARATION OF 1-BROMO-3,5-DICHLOROBENZENE BASF Aktiengesellschaft (DE) 1983-07-06 EP disclosed
EP-0046859-A1 Process for the preparation of 1-bromo-3,5-dichlorobenzene BASF Aktiengesellschaft (DE) 1982-03-10 EP disclosed
EP-0046859-A1 Process for the preparation of 1-bromo-3,5-dichlorobenzene BASF Aktiengesellschaft (DE) 1982-03-10 EP disclosed
US-4075007-A N-chloro-chloroacetamides as herbicides NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1978-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298781-A1 COMPOUNDS FOR THE INHIBITION OF APOPTOSIS BAX, BCL2, CASP3 MAPT 1796/4885KMT2A 4770/4885CYP1A2 2273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.