Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410230 | 0.86 | PDE7A (0.42) | EPHX2TNFRSF1APPARGNPFFR1NPFFR2 | |
| SCHEMBL1410096 | 0.85 | ALDH1A1 (0.40) | EPHX2TNFRSF1APPARGNPFFR1NPFFR2 | |
| SCHEMBL1409350 | 0.79 | MAPT (0.40) | ALDH1A1HPGDMAPTHTTMEN1 | |
| SCHEMBL1410092 | 0.77 | MAPT (0.40) | EPHX2PPARGALDH1A1MAPTMEN1 | |
| SCHEMBL14300699 | 0.77 | ALDH1A1 (0.57) | TNFRSF1ANPFFR1NPFFR2ALDH1A1HPGD | |
| SCHEMBL14300698 | 0.77 | ALDH1A1 (0.57) | TNFRSF1ANPFFR1NPFFR2ALDH1A1HPGD | |
| SCHEMBL1410152 | 0.76 | KDM4E (0.62) | ALDH1A1HPGDMAPTHTTNPSR1 | |
| SCHEMBL1410157 | 0.76 | ALDH1A1 (0.46) | TNFRSF1AALDH1A1HPGDMAPTHTT | |
| SCHEMBL1410156 | 0.76 | TDP1 (0.40) | TNFRSF1ANPFFR1NPFFR2ALDH1A1HPGD | |
| SCHEMBL1410414 | 0.74 | KDM4E (0.47) | ALDH1A1HPGDMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | NES, BMI1, DOT1L | EPHX2 254/4885TNFRSF1A 4817/4885PPARG 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.