Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1410228 | 0.86 | PDE7A (0.48) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL1410095 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL1409349 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL1410091 | 0.78 | RPA1 (0.43) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL1410151 | 0.77 | CYP1A2 (0.57) | ALDH1A1HPGDGAATDP1KDM4E | |
| SCHEMBL1410158 | 0.76 | EPHX2 (0.41) | ALDH1A1MAPTHPGDHTTNPSR1 | |
| SCHEMBL1410412 | 0.75 | RXRA (0.44) | ALDH1A1HPGDTDP1KDM4ESLC9A1 | |
| SCHEMBL1409528 | 0.74 | RXRA (0.45) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL1410592 | 0.74 | RXRA (0.48) | ALDH1A1HPGDTDP1KDM4ESLC9A1 | |
| SCHEMBL14300699 | 0.73 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251187-A1 | HETEROCYCLIC COMPOUND | NES, BMI1, DOT1L | ALDH1A1 270/4885MAPT 3305/4885HPGD 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.