Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255416 | 1.00 | CHRM5 (0.65) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL17272396 | 0.98 | CHRM5 (0.62) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10176 | 0.98 | CHRM5 (0.62) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL10614451 | 0.98 | CHRM5 (0.62) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL11130645 | 0.93 | CHRM5 (0.62) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL13381313 | 0.89 | CHRM5 (0.58) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 | |
| SCHEMBL22266307 | 0.85 | SIGMAR1 (0.50) | CHRM5CHRM3SIGMAR1SMN1; SMN2 | |
| SCHEMBL13214851 | 0.84 | ALDH1A1 (0.46) | CHRM5CHRM3SIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL22266338 | 0.83 | SIGMAR1 (0.48) | CHRM5CHRM3SIGMAR1ALDH1A1 | |
| SCHEMBL25134502 | 0.83 | SIGMAR1 (0.48) | CHRM5CHRM3SIGMAR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098056-A2 | HIGH RELAXIVITY CHELATES | EPIX PHARMACEUTICALS, INC. (US) | 2008-08-14 | — | — | WO | disclosed |