Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2778301 | 0.98 | TDP1 (0.79) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL28093034 | 0.98 | TDP1 (0.79) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL2777961 | 0.98 | TDP1 (0.79) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL2777301 | 0.98 | TDP1 (0.79) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL7292310 | 0.94 | TDP1 (0.78) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL223441 | 0.90 | TDP1 (1.00) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL14613137 | 0.90 | TDP1 (0.66) | TDP1LMNAALDH1A1NPC1RAB9A | |
| SCHEMBL2069111 | 0.88 | TDP1 (0.96) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL225815 | 0.88 | TDP1 (0.96) | TDP1LMNAMAPK1HIF1ASLC6A2 | |
| SCHEMBL17466182 | 0.88 | TDP1 (0.96) | TDP1LMNAMAPK1HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | claimed |
| CN-105683194-A | (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones as inhibitors of fibrinolysis | 拜耳制药股份公司 | 2016-06-15 | — | — | CN | claimed |
| US-11708320-B2 | Environmentally-friendly hydroazidation of olefins | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-20210284601-A1 | ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2021-09-16 | — | — | US | disclosed |
| CN-105683194-B | The inhibitor of (azepine) pyrido PyrazolopyrimidinonecGMP and indazole hepyramine as fibrinolysis | 拜耳制药股份公司 | 2018-09-14 | — | — | CN | disclosed |
| CN-107108638-A | Piperidyl PyrazolopyrimidinonecGMP and application thereof | 拜耳制药股份公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105683194-A | (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones as inhibitors of fibrinolysis | 拜耳制药股份公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-103127402-A | Application of swallow cimitin in preparation of whitening and freckle removing product | YANG YANJIAO | 2013-06-05 | — | — | CN | disclosed |
| CN-102712933-A | regulated expression system | PROYECTO BIOMEDICINA CIMA SL | 2012-10-03 | — | — | CN | disclosed |
| CN-102112616-A | System for packaging high-capacity adenoviruses | PROYECTO BIOMEDICINA CIMA SL | 2011-06-29 | — | — | CN | disclosed |
| CN-102099481-A | Self-inactivating helper adenoviruses for production of high-capacity recombinant adenoviruses | PROYECTO BIOMEDICINA CIMA SL | 2011-06-15 | — | — | CN | disclosed |
| US-20050256051-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | THE POPULATION COUNCIL, INC. (US) | 2005-11-17 | — | — | US | disclosed |
| EP-1392366-A4 | NUCLEAR RECEPTOR-MEDIATED INTRODUCTION OF A PNA INTO CELL NUCLEI | POPULATION COUNCIL INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1392366-A1 | NUCLEAR RECEPTOR-MEDIATED INTRODUCTION OF A PNA INTO CELL NUCLEI | THE POPULATION COUNCIL, INC. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20030096739-A1 | Nuclear receptor-mediated introduction of a PNA into cell nuclei | POPULATION COUNCIL, INC., THE | 2003-05-22 | — | — | US | disclosed |
| WO-2002083186-A1 | NUCLEAR RECEPTOR-MEDIATED INTRODUCTION OF A PNA INTO CELL NUCLEI | THE POPULATION COUNCIL, INC. (US) | 2002-10-24 | — | — | WO | disclosed |
| EP-0822991-A4 | METHODS, POLYPEPTIDES, NUCLEOTIDE SEQUENCE OF XOR-6, A VITAMIN D-LIKE RECEPTOR FROM XENOPUS | SALK INST FOR BIOLOGICAL STUDI (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999032649-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL 1,3-AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0822991-A1 | METHODS, POLYPEPTIDES, NUCLEOTIDE SEQUENCE OF XOR-6, A VITAMIN D-LIKE RECEPTOR FROM XENOPUS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996022390-A1 | METHODS, POLYPEPTIDES, NUCLEOTIDE SEQUENCE OF XOR-6, A VITAMIN D-LIKE RECEPTOR FROM XENOPUS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1996-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11708320-B2 | Environmentally-friendly hydroazidation of olefins | HAO2, AHR, HMOX1 | TDP1 2142/4885LMNA 4815/4885MAPK1 2501/4885 |
| US-20210284601-A1 | ENVIRONMENTALLY-FRIENDLY HYDROAZIDATION OF OLEFINS | HAO2, AHR, HMOX1 | TDP1 2142/4885LMNA 4815/4885MAPK1 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.