Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723485 | 0.91 | MEN1 (0.39) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4721827 | 0.91 | PDE4A (0.35) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4722814 | 0.86 | MEN1 (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4720525 | 0.83 | CCR9 (0.33) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4720482 | 0.83 | MEN1 (0.34) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4722898 | 0.83 | MEN1 (0.35) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4723628 | 0.83 | MEN1 (0.36) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4723938 | 0.83 | MEN1 (0.34) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4724438 | 0.81 | L3MBTL1 (0.34) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4720610 | 0.81 | MEN1 (0.33) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |