Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.31 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721827 | 0.92 | PDE4A (0.35) | CCR9PIK3C3PDE4APDE4BPDE4C | |
| SCHEMBL4722814 | 0.87 | MEN1 (0.36) | CCR9PIK3C3PDE4APDE4BPDE4C | |
| SCHEMBL4719259 | 0.87 | L3MBTL1 (0.33) | CCR9JAK2JAK1TYK2 | |
| SCHEMBL4724438 | 0.85 | L3MBTL1 (0.34) | CCR9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4723628 | 0.84 | MEN1 (0.36) | CCR9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4723938 | 0.84 | MEN1 (0.34) | CCR9PIK3C3PDE4APDE4BPDE4C | |
| SCHEMBL4723485 | 0.83 | MEN1 (0.39) | PIK3C3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4723604 | 0.83 | MEN1 (0.34) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL4719128 | 0.83 | L3MBTL1 (0.33) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL14101914 | 0.83 | PDE4A (0.35) | PIK3C3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |