SCHEMBL14102192

SCHEMBL14102192

Clc1ccc2c(c1)CCc1cccnc1C2OCCCc1c[nH]cn1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 11/20 0.45
FNTB P49356 11/20 0.45
SLC6A15 Q9H2J7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14102073 0.84 MEN1 (0.44) FNTAFNTB
SCHEMBL14102194 0.80 MEN1 (0.44) FNTAFNTB
SCHEMBL14102015 0.80 FNTA (0.53) FNTAFNTB
SCHEMBL14102080 0.79 FNTA (0.52) FNTAFNTB
SCHEMBL14102087 0.79 MEN1 (0.49) FNTAFNTBSLC6A15
SCHEMBL14102016 0.79 MEN1 (0.46) FNTAFNTB
SCHEMBL14101997 0.79 MEN1 (0.50) FNTAFNTB
SCHEMBL14102019 0.78 FNTA (0.55) FNTAFNTB
SCHEMBL14102196 0.78 MEN1 (0.53) FNTAFNTBSLC6A15
SCHEMBL4696153 0.78 FNTA (0.65) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1318993-B1 SUBSTITUTED IMIDAZOLES AS DUAL HISTAMINE H1 AND H3 AGONISTS OR ANTAGONISTS SCHERING CORP (US) 2008-08-20 EP disclosed