Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 5/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688741 | 0.84 | L3MBTL1 (0.45) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL803116 | 0.81 | NPSR1 (0.41) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL31059170 | 0.81 | NPSR1 (0.41) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL2930274 | 0.81 | CDK1 (0.42) | TDP1TSHRLMNAALDH1A1MGMT | |
| SCHEMBL9804043 | 0.81 | CDK1 (0.55) | TSHRLMNAMGMTCDK1CCNB1 | |
| SCHEMBL28633887 | 0.80 | NPSR1 (0.38) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL29552357 | 0.79 | ADORA1 (0.41) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL20394079 | 0.79 | ADORA1 (0.41) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL25496358 | 0.78 | NPSR1 (0.36) | L3MBTL1ATMTDP1NPSR1TSHR | |
| SCHEMBL20394023 | 0.78 | NPSR1 (0.36) | L3MBTL1ATMTDP1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100447-A2 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2008-08-21 | — | — | WO | disclosed |