SCHEMBL30688741

SCHEMBL30688741

O=C(Oc1ncnc2[nH]cnc12)N(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NPSR1 Q6W5P4 2/20 0.39
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
ALDH1A1 P00352 1/20 0.38
EGFR P00533 1/20 0.35
CSF1R P07333 1/20 0.35
MAP3K7 O43318 2/20 0.33
TAB1 Q15750 2/20 0.33
TRPA1 O75762 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM3 P20309 1/20 0.33
MAOB P27338 1/20 0.33
BRD4 O60885 1/20 0.33
CDC7 O00311 1/20 0.32
DBF4 Q9UBU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14102460 0.84 L3MBTL1 (0.42) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL2938155 0.80 BRD4 (0.40) TDP1TSHRLMNAALDH1A1TRPA1
SCHEMBL2314712 0.78 PARP1 (0.33) MAP3K7TAB1TRPA1BRD4
SCHEMBL803116 0.77 NPSR1 (0.41) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL31059170 0.77 NPSR1 (0.41) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL28633887 0.76 NPSR1 (0.38) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL3038559 0.76 CSF1R (0.39) L3MBTL1NPSR1LMNAALDH1A1EGFR
SCHEMBL29775862 0.75 PARP1 (0.36) MAP3K7TAB1
SCHEMBL29552357 0.75 ADORA1 (0.41) L3MBTL1ATMTDP1NPSR1TSHR
SCHEMBL20394079 0.75 ADORA1 (0.41) L3MBTL1ATMTDP1NPSR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025060642-A1 MODIFIED NUCLEOTIDE COMPOUND, OLIGONUCLEOTIDE THEREOF, AND USE THEREOF 广州必贝特医药股份有限公司 2025-03-27 WO disclosed
CN-118063533-B Modified nucleotide compound, oligonucleotide and application thereof 广州必贝特医药股份有限公司 2024-08-27 CN disclosed
CN-118063533-A Modified nucleotide compound, oligonucleotide and application thereof 广州必贝特医药股份有限公司 2024-05-24 CN disclosed
CN-110678447-B Modified nucleic acid monomer compounds and oligonucleotide analogues 卫材R&D管理有限公司 2023-12-12 CN disclosed