Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4893146 | 0.91 | EPHX2 (0.44) | EPHX2KDM4ENPC1RAB9AHTT | |
| SCHEMBL14103619 | 0.84 | RAB9A (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14103622 | 0.83 | ALDH1A1 (0.45) | KDM4EHTTNAMPTALDH1A1 | |
| SCHEMBL14103621 | 0.80 | NAMPT (0.52) | KDM4ENAMPTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL14103272 | 0.79 | KDM4E (0.41) | KDM4EHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL4889436 | 0.76 | NPC1 (0.40) | KDM4ENPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL4892221 | 0.76 | ALDH1A1 (0.48) | KDM4ENPC1RAB9AHTTSMN1; SMN2 | |
| SCHEMBL14102822 | 0.75 | KDM4E (0.43) | KDM4EHTTMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4896179 | 0.75 | RAB9A (0.58) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4884232 | 0.73 | ALDH1A1 (0.47) | KDM4EHTTNAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098859-A1 | HCV POLYMERASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | disclosed |