SCHEMBL14103263

SCHEMBL14103263

CC(C)CC(O)=C1C(=O)OC(C)(C)OC1=O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 7/20 0.58
▸ CDC25B P30305 5/20 0.53
▸ ACP1 P24666 4/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.43
▸ ALDH1A1 P00352 6/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.34
▸ HTT P42858 1/20 0.32
▸ PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1356857 0.78 PTPN1 (0.62) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL17748526 0.76 PTPN1 (0.56) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL14194487 0.76 PTPN1 (0.57) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL20351495 0.76 PTPN1 (0.56) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL20826561 0.74 PTPN1 (0.86) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL7114676 0.74 PTPN1 (0.74) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL3590452 0.74 PTPN1 (1.00) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL1028277 0.73 PTPN1 (0.53) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL12332317 0.73 PTPN1 (0.53) PTPN1CDC25BACP1L3MBTL1ALDH1A1
SCHEMBL12018164 0.71 POLB (0.41) ALDH1A1CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743174-A1 MODULATORS OF CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY Aconcagua Bio, Inc. (US) 2026-05-20 — — EP disclosed
US-20250042916-A1 COMPOUNDS, COMPOSITIONS, AND METHODS ACONCAGUA BIO, INC. 2025-02-06 — — US disclosed
WO-2025015268-A1 MODULATORS OF CALCITONIN RECEPTOR AND/OR AMYLIN RECEPTOR ACTIVITY ACONCAGUA BIO, INC. (US) 2025-01-16 — — WO disclosed
US-11801242-B2 Compositions and methods for adjuvant cancer therapeutics DUKE UNIVERSITY (US) 2023-10-31 — — US disclosed
US-11801242-B2 Compositions and methods for adjuvant cancer therapeutics DUKE UNIVERSITY (US) 2023-10-31 — — US disclosed
US-20220008408-A1 COMPOSITIONS AND METHODS FOR ADJUVANT CANCER THERAPEUTICS DUKE UNIVERSITY (US) 2022-01-13 — — US disclosed
US-7396936-B1 Modulators of calcitonin and amylin receptor activity KEMIA, INC. (US) 2008-07-08 — — US disclosed
US-7396936-B1 Modulators of calcitonin and amylin receptor activity KEMIA, INC. (US) 2008-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220008408-A1 COMPOSITIONS AND METHODS FOR ADJUVANT CANCER THERAPEUTICS TP53, PLK1, NRAS PTPN1 2014/4885CDC25B 462/4885ACP1 619/4885
US-11801242-B2 Compositions and methods for adjuvant cancer therapeutics TP53, PLK1, NRAS PTPN1 2014/4885CDC25B 462/4885ACP1 619/4885
US-20250042916-A1 COMPOUNDS, COMPOSITIONS, AND METHODS IAPP, GIPR, GPR119 PTPN1 1772/4885CDC25B 4381/4885ACP1 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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