Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679736 | 0.77 | RAB9A (0.92) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL5821824 | 0.76 | RAB9A (0.62) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL733677 | 0.76 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL17396888 | 0.75 | RAB9A (0.71) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL540861 | 0.75 | RAB9A (0.60) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL2825796 | 0.74 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL10159091 | 0.74 | RAB9A (0.66) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL735099 | 0.73 | HTR2A (0.68) | RAB9ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27320852 | 0.73 | RAB9A (0.64) | RAB9ASMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL6465788 | 0.72 | HTR2A (0.88) | RAB9ASMN1; SMN2HTR2AHTR1ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405212-B2 | Helix mimetics and composition and methods related thereto | MYRIAD GENETICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |