Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679736 | 0.76 | RAB9A (0.92) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL14106331 | 0.75 | RAB9A (0.62) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL5821824 | 0.75 | RAB9A (0.62) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL733677 | 0.75 | RAB9A (0.69) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL27320852 | 0.74 | RAB9A (0.64) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL17396888 | 0.74 | RAB9A (0.71) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL9033157 | 0.73 | HTR2A (0.74) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL2825796 | 0.73 | RAB9A (0.70) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL10159091 | 0.73 | RAB9A (0.66) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL28709084 | 0.72 | MAPT (0.61) | RAB9ASMN1; SMN2MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2413696-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | Mount Sinai School Of Medicine Of New York University (US) | 2012-02-08 | — | — | EP | claimed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | claimed |
| EP-2413696-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | Mount Sinai School Of Medicine Of New York University (US) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010114636-A1 | COMPOSITIONS FOR TREATMENT OF ALZHEIMER'S DISEASE | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2010-10-07 | — | — | WO | disclosed |