Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850745 | 0.84 | CYP2A6 (0.47) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL27398530 | 0.79 | CYP2A6 (0.55) | AGXTCYP2A6 | |
| SCHEMBL1272861 | 0.78 | CYP2A6 (0.55) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL3150291 | 0.78 | AGXT (0.68) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL5319433 | 0.77 | AGXT (0.72) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL4909971 | 0.77 | CA2 (0.55) | AGXTCA2PTGS2 | |
| SCHEMBL4909976 | 0.77 | CA2 (0.42) | AGXTCA2PTGS2SLC9A1 | |
| SCHEMBL2060860 | 0.76 | AGXT (0.49) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL14035938 | 0.75 | AGXT (0.64) | AGXTCYP2A6ASIC3LOXL2ADRB2 | |
| SCHEMBL2088811 | 0.74 | AGXT (0.68) | AGXTCYP2A6ASIC3LOXL2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393865-B2 | Sleep inducing compounds and methods relating thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2008-07-01 | — | — | US | disclosed |