Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLQ | O75417 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4705712 | 0.89 | POLQ (0.49) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL13824325 | 0.83 | POLQ (0.49) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL14192258 | 0.82 | KMT2A (0.49) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL4294754 | 0.80 | KMT2A (0.54) | KDM4EKMT2APOLQCYP3A4CYP2C19 | |
| SCHEMBL24435364 | 0.79 | KDM4E (0.46) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL4107217 | 0.78 | ALDH1A1 (0.46) | KDM4EKMT2AAOC3HTTGAA | |
| SCHEMBL12763807 | 0.78 | KDM4E (0.45) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL16353748 | 0.78 | KDM4E (0.49) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL7502077 | 0.77 | ALDH1A1 (0.41) | KDM4EAOC3HTT | |
| SCHEMBL7506948 | 0.77 | POLQ (0.48) | KDM4EPOLQAOC3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417152-B2 | 4-bromo-5-(2-chloro-benzoylamino)-1H-pyrazole-3-carboxylic acid amide derivatives and related compounds as bradykinin B1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. (US) | 2008-08-26 | — | — | US | disclosed |