Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLQ | O75417 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192258 | 0.85 | KMT2A (0.49) | KDM4EKMT2APOLQNPY5RCHRM5 | |
| SCHEMBL16353748 | 0.84 | KDM4E (0.49) | KDM4EKMT2APOLQNPY5RCHRM5 | |
| SCHEMBL3399855 | 0.81 | TP53 (0.65) | KDM4EKMT2APOLQTP53ALDH1A1 | |
| SCHEMBL16353651 | 0.81 | KDM4E (0.46) | KDM4EKMT2APOLQNPY5RCHRM5 | |
| SCHEMBL2435091 | 0.80 | NOTUM (0.56) | KMT2APOLQNPY5RTP53HPGD | |
| SCHEMBL14108177 | 0.79 | KDM4E (0.47) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL2202823 | 0.78 | KDM4E (0.62) | KDM4EKMT2ANPY5RALDH1A1RAB9A | |
| SCHEMBL13824325 | 0.78 | POLQ (0.49) | KDM4EKMT2APOLQCHRM5CHKA | |
| SCHEMBL22170065 | 0.78 | DRD4 (0.44) | KMT2APOLQTP53ALDH1A1RAB9A | |
| SCHEMBL10258229 | 0.78 | TP53 (0.43) | KDM4EKMT2ATP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | ENODIA THERAPEUTICS SAS (FR) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153732-A1 | PROTEIN SECRETION INHIBITORS | SEC61B, SEC61A1, SEC61G | KDM4E 4710/4885KMT2A 4802/4885POLQ 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.