Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.45 |
| ▸ | HSF1 | Q00613 | 5/20 | 0.45 |
| ▸ | XDH | P47989 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110504 | 0.92 | FAAH (0.51) | FAAHCES1RAB9ATP53DAGLA | |
| SCHEMBL14110574 | 0.89 | FAAH (0.47) | FAAHCES1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14110460 | 0.83 | XDH (0.46) | SMN1; SMN2RAB9ANPC1TP53HSF1 | |
| SCHEMBL6463072 | 0.83 | DAGLA (0.60) | FAAHCES1DAGLAXDH | |
| SCHEMBL5581487 | 0.83 | FAAH (0.45) | FAAHCES1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14110405 | 0.83 | FAAH (0.44) | FAAHCES1RAB9ANPC1DAGLA | |
| SCHEMBL14110434 | 0.82 | DAGLA (0.47) | RAB9ADAGLAHSF1XDH | |
| SCHEMBL14110447 | 0.82 | KMT2A (0.46) | SMN1; SMN2RAB9ANPC1TP53XDH | |
| SCHEMBL14110443 | 0.81 | FAAH (0.50) | FAAHSMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL5520519 | 0.80 | FAAH (0.43) | FAAHCES1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744755-B1 | COMPOUNDS AND COMPOSITIONS AS CATHEPSIN S INHIBITORS | IRM LLC (BM) | 2012-12-05 | — | — | EP | claimed |