Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.47 |
| ▸ | CTSL | P07711 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12196292 | 0.82 | CTSS (0.49) | CTSSCTSLCTSKRENALDH1A1 | |
| SCHEMBL12196236 | 0.82 | CTSS (0.49) | CTSSCTSLCTSKRENALDH1A1 | |
| SCHEMBL8289701 | 0.81 | CTSS (0.48) | CTSSCTSLCTSKREN | |
| SCHEMBL12196239 | 0.76 | CTSS (0.47) | CTSSCTSLCTSKRENALDH1A1 | |
| SCHEMBL2162740 | 0.76 | CTSS (0.43) | CTSSCTSLCTSKRENCTSB | |
| SCHEMBL8290883 | 0.74 | CTSS (0.48) | CTSSCTSLCTSKRENALDH1A1 | |
| SCHEMBL12196312 | 0.74 | CTSK (0.58) | CTSSCTSLCTSK | |
| SCHEMBL2163908 | 0.74 | CTSK (0.58) | CTSSCTSLCTSK | |
| SCHEMBL12196307 | 0.73 | CTSS (0.53) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12196296 | 0.73 | CTSS (0.56) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1744755-B1 | COMPOUNDS AND COMPOSITIONS AS CATHEPSIN S INHIBITORS | IRM LLC (BM) | 2012-12-05 | — | — | EP | claimed |