Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.77 |
| ▸ | KLK7 | P49862 | 1/20 | 0.77 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Castanin SCHEMBL572274 | 0.87 | RAB9A (1.00) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| SCHEMBL18825571 | 0.87 | HDAC6 (0.70) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| SCHEMBL2971118 | 0.87 | XDH (0.76) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| Glycitein SCHEMBL4725635 | 0.85 | HDAC6 (0.78) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| Xenognosin B SCHEMBL72611 | 0.84 | KDM4E (0.83) | RAB9AHDAC6KDM4EALDH1A1HPGD | |
| Xenognosin B SCHEMBL30851576 | 0.84 | KDM4E (0.83) | RAB9AHDAC6KDM4EALDH1A1HPGD | |
| Glycitein SCHEMBL7733712 | 0.83 | HDAC6 (1.00) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| Glycitein SCHEMBL19720 | 0.83 | HDAC6 (1.00) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| Glycitein SCHEMBL29497281 | 0.83 | HDAC6 (1.00) | RAB9AKLK7HDAC6KDM4EALDH1A1 | |
| SCHEMBL5426172 | 0.83 | HDAC6 (0.81) | RAB9AKLK7HDAC6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633203-B2 | Use of pterocarpans as active anti-cellulite ingredients | SYMRISE AG (DE) | 2014-01-21 | — | — | US | claimed |
| EP-2295031-B1 | Use of pterocarpans as anti-cellulite agents | SYMRISE AG (DE) | 2018-01-10 | — | — | EP | disclosed |
| EP-2295031-A2 | Use of pterocarpans as anti-cellulite agents | Symrise AG (DE) | 2011-03-16 | — | — | EP | disclosed |