Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661040 | 1.00 | NFKB1 (0.45) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL13525107 | 0.86 | SIRT6 (0.49) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL20435333 | 0.85 | SIRT6 (0.55) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14978808 | 0.85 | SIRT6 (0.55) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL16748603 | 0.84 | MAPT (0.59) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL468725 | 0.84 | MAPT (0.59) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL468726 | 0.84 | MAPT (0.59) | NFKB1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL1741357 | 0.83 | SIRT6 (0.58) | MAPTSIRT6SIRT1CHRM1PLA2G2C | |
| SCHEMBL6367910 | 0.82 | CYP2C9 (0.43) | NFKB1ALDH1A1HDAC7HDAC8HDAC6 | |
| SCHEMBL6693093 | 0.82 | NFKB1 (0.42) | NFKB1KDM4EMAPTTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396897-B2 | N-α- and N-ε-lysine and ornithine compounds comprising a thiol function and cosmetic use thereof | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |