Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADK | P55263 | 4/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13598694 | 0.89 | ADORA3 (0.52) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111460 | 0.89 | ADORA3 (0.38) | HIF1AADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL14111500 | 0.88 | HIF1A (0.43) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111471 | 0.88 | ADORA3 (0.40) | HIF1AADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL14111576 | 0.86 | HIF1A (0.42) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111447 | 0.86 | HIF1A (0.42) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111747 | 0.86 | ADORA2A (0.49) | ADORA2AADKPAX8 | |
| SCHEMBL14111440 | 0.86 | ADORA2A (0.49) | ADORA2AADKPAX8 | |
| SCHEMBL14111453 | 0.84 | HIF1A (0.42) | HIF1ATP53STAT6ADORA3ADORA2A | |
| SCHEMBL14111449 | 0.84 | TMEM97 (0.49) | HIF1ATP53STAT6ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |