Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.62 |
| ▸ | VDR | P11473 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112646 | 1.00 | MAPT (0.62) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL7264390 | 0.90 | VDR (0.69) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL14112623 | 0.90 | MAPT (0.62) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL14112622 | 0.90 | MAPT (0.62) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL16317843 | 0.90 | MAPT (0.62) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL14112644 | 0.89 | VDR (0.66) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL5433646 | 0.88 | VDR (0.60) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL5437551 | 0.88 | VDR (0.60) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL8090430 | 0.88 | MAPT (0.57) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| SCHEMBL8769851 | 0.87 | MAPT (0.60) | MAPTSMN1; SMN2SREBF1VDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171728-A1 | Efficient Process for Preparing Steroids and Vitamin D Derivatives With the Unnatural Configuration at C20 (20 Alpha-Methyl) from Pregnenolone | QUATRX PHARMACEUTICALS CO. | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171728-A1 | Efficient Process for Preparing Steroids and Vitamin D Derivatives With the Unnatural Configuration at C20 (20 Alpha-Methyl) from Pregnenolone | CYP2R1, CYP24A1, VDR | MAPT 4708/4885SMN1; SMN2 4629/4885SREBF1 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.