SCHEMBL1411274

SCHEMBL1411274

CCCCOC(=O)c1ccc(NC(=O)CON)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.68
RECQL P46063 1/20 0.68
RAB9A P51151 5/20 0.60
NPC1 O15118 2/20 0.59
CASP1 P29466 1/20 0.59
LMNA P02545 3/20 0.58
CYP1A2 P05177 2/20 0.58
TSHR P16473 2/20 0.58
CYP2C19 P33261 2/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
PDE4D Q08499 1/20 0.58
MAPT P10636 4/20 0.57
TDP1 Q9NUW8 1/20 0.57
ALDH1A1 P00352 5/20 0.57
SMN1; SMN2 Q16637 5/20 0.56
MAPK1 P28482 2/20 0.56
ESR1 P03372 1/20 0.56
CYP2D6 P10635 1/20 0.56
NR1H2 P55055 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1411400 0.86 RAB9A (0.76) HPGDRAB9ANPC1LMNACYP1A2
SCHEMBL5947201 0.83 HPGD (0.76) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL7937664 0.83 HPGD (0.72) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL10943133 0.81 RAB9A (0.86) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL10943491 0.81 HPGD (0.78) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL1411294 0.81 MEN1 (0.72) HPGDRAB9ANPC1LMNAMAPT
SCHEMBL8162691 0.81 HPGD (0.72) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL3428262 0.81 HPGD (0.72) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL10940888 0.79 HPGD (0.74) HPGDRECQLRAB9ANPC1CASP1
SCHEMBL4918746 0.79 HPGD (0.74) HPGDRECQLRAB9ANPC1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2056106-B1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO (JP) 2017-10-11 EP claimed
US-9340651-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-05-17 US claimed
WO-2015033743-A1 METHOD FOR PREPARING LABELED SUGAR CHAIN SAMPLE 住友ベークライト株式会社 (JP) 2015-03-12 WO claimed
EP-2518495-A2 Sugar chain-capturing substance and use thereof Sumitomo Bakelite Company, Ltd. (JP) 2012-10-31 EP claimed
US-20110089033-A1 METHOD OF PREPARING SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD OF ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-04-21 US claimed
EP-2295962-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN Sumitomo Bakelite Co., Ltd. (JP) 2011-03-16 EP claimed
WO-2009150834-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN 住友ベークライト株式会社 (JP) 2009-12-17 WO claimed
US-20090306291-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2009-12-10 US claimed
EP-2056106-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF Sumitomo Bakelite Company, Ltd. (JP) 2009-05-06 EP claimed
EP-2056106-B1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO (JP) 2017-10-11 EP disclosed
US-9714328-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY, LTD. (JP) 2017-07-25 US disclosed
US-9340651-B2 Sugar chain-capturing substance and use thereof SUMITOMO BAKELITE COMPANY LIMITED (JP) 2016-05-17 US disclosed
WO-2015033743-A1 METHOD FOR PREPARING LABELED SUGAR CHAIN SAMPLE 住友ベークライト株式会社 (JP) 2015-03-12 WO disclosed
EP-2799868-A2 Sugar chain-capturing substance and use thereof Sumitomo Bakelite Co., Ltd. (JP) 2014-11-05 EP disclosed
EP-2503332-A2 Sugar chain-capturing substance and use thereof Sumitomo Bakelite Company, Ltd. (JP) 2012-09-26 EP disclosed
US-20110089033-A1 METHOD OF PREPARING SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD OF ANALYZING SUGAR CHAIN SUMITOMO BAKELITE CO., LTD. (JP) 2011-04-21 US disclosed
EP-2295962-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN Sumitomo Bakelite Co., Ltd. (JP) 2011-03-16 EP disclosed
WO-2009150834-A1 METHOD FOR PREPARATION OF SUGAR CHAIN SAMPLE, SUGAR CHAIN SAMPLE, AND METHOD FOR ANALYSIS OF SUGAR CHAIN 住友ベークライト株式会社 (JP) 2009-12-17 WO disclosed
US-20090306291-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2009-12-10 US disclosed
EP-2056106-A1 SUGAR CHAIN-CAPTURING SUBSTANCE AND USE THEREOF Sumitomo Bakelite Company, Ltd. (JP) 2009-05-06 EP disclosed