Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14183047 | 1.00 | DNM1 (0.38) | DNM1EPHX1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL23058658 | 1.00 | DNM1 (0.38) | DNM1EPHX1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL18103501 | 0.94 | DNM1 (0.41) | DNM1EPHX1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL21872492 | 0.92 | EPHX1 (0.42) | DNM1EPHX1ALDH1A1TSHRFDPS | |
| SCHEMBL10885151 | 0.92 | EPHX1 (0.42) | DNM1EPHX1ALDH1A1TSHRFDPS | |
| SCHEMBL20822491 | 0.90 | EPHX1 (0.46) | DNM1EPHX1TSHRFDPSLMNA | |
| SCHEMBL3838865 | 0.90 | EPHX1 (0.46) | DNM1EPHX1TSHRFDPSLMNA | |
| SCHEMBL28997938 | 0.90 | EPHX1 (0.46) | DNM1EPHX1TSHRFDPSLMNA | |
| SCHEMBL13478425 | 0.89 | DNM1 (0.43) | DNM1EPHX1ALDH1A1TSHRCYP3A4 | |
| SCHEMBL8235653 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-A1 | VLA-4 INHIBITORY DRUG | Daiichi Sankyo Company, Limited (JP) | 2008-08-27 | — | — | EP | disclosed |