Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA6 | P17658 | 2/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.36 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.36 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12597850 | 0.88 | MAP2K1 (0.47) | KCNA6KCNA3KCNA4KCNA5KCNA2 | |
| Hydrochloric Acid SCHEMBL1518077 | 0.87 | MAP2K1 (0.47) | KCNA6KCNA3KCNA4KCNA5KCNA2 | |
| SCHEMBL12764728 | 0.81 | VIP (0.49) | KCNA6KCNA3KCNA4KCNA5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1518416 | 0.80 | VIP (0.48) | KCNA6KCNA3KCNA4KCNA5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1518116 | 0.78 | KCNA6 (0.46) | KCNA6KCNA3KCNA4KCNA5KDM4E | |
| Hydrochloric Acid SCHEMBL1518215 | 0.75 | HDAC3 (0.49) | NT5EKDM4EHDAC1HDAC2HDAC3 | |
| Dihydrosventrin SCHEMBL12559819 | 0.72 | CBLB (0.38) | KDM4EHSD17B10ALDH1A1HDAC1HDAC2 | |
| SCHEMBL13803749 | 0.72 | HDAC1 (0.36) | KDM4EHSD17B10ALDH1A1HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL1518217 | 0.71 | CBLB (0.39) | KDM4EALDH1A1HDAC1HDAC2HDAC3 | |
| Dihydrosventrin SCHEMBL1518647 | 0.71 | CBLB (0.38) | KDM4EHSD17B10ALDH1A1HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008094479-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |