⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411589 | 0.95 | — | — | |
| SCHEMBL11326433 | 0.95 | — | — | |
| SCHEMBL1411615 | 0.84 | — | — | |
| SCHEMBL22715250 | 0.80 | — | — | |
| SCHEMBL4923961 | 0.70 | — | — | |
| SCHEMBL31189298 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL16860543 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL16860542 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL18112474 | 0.67 | — | — | |
| SCHEMBL16843009 | 0.64 | ACHE (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354849-A | Imine compound, preparation method and application thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-0138669-B1 | PROCESS FOR THE PREPARATION OF SILANES FROM METHYLDICHLOROSILANE AND CHLOROSILANES | RHONE-POULENC CHIMIE (FR) | 1988-08-10 | — | — | EP | claimed |
| EP-0138670-B1 | PROCESS FOR THE PREPARATION OF SILANES WITH A SI-H BOND BY REDISTRIBUTION | RHONE-POULENC CHIMIE (FR) | 1988-05-25 | — | — | EP | claimed |
| US-4746752-A | QUATERNARY OR TERTIARY AMINE CATALYST | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1988-05-24 | — | — | US | claimed |
| US-4605543-A | DISTRIBUTION AND DISPROPORTIONATION CATALYSIS | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1986-08-12 | — | — | US | claimed |
| CN-115190815-B | Arylcyclohexylamine derivatives and their use in the treatment of psychotic disorders | 吉尔伽美什制药公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-112424157-B | Method for synthesizing and purifying (2R, 6R) -hydroxynorketamine | 美国政府健康及人类服务部 | 2024-02-20 | — | — | CN | disclosed |
| CN-111971288-B | Selective inhibitors of protein arginine methyltransferase 5 (PRMT 5) | 普莱鲁德疗法有限公司 | 2023-12-01 | — | — | CN | disclosed |
| EP-3765461-B1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS INC (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116354849-A | Imine compound, preparation method and application thereof | 江苏恩华药业股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-115190815-A | Arylcyclohexylamine derivatives and their use in the treatment of psychotic disorders | 吉尔伽美什制药公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-114989142-A | Preparation method of pyrazole compound | 沈阳万菱生物技术有限公司 | 2022-09-02 | — | — | CN | disclosed |
| EP-0070463-B1 | PROCESS FOR THE PREPARATION OF ACID HALIDES | BAYER AG (DE) | 1985-01-09 | — | — | EP | disclosed |
| US-4452943-A | ADDING NITRILE-CONTAINING MATERIAL TO NON-POLAR THERMOPLASTIC POLYMER | GOLDMAN CONRAD | 1984-06-05 | — | — | US | disclosed |
| US-4410529-A | HYPOTENSIVE AGNENTS, ANTICOAGULANTS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-18 | — | — | US | disclosed |
| EP-0070463-A1 | Process for the preparation of acid halides | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0042107-A1 | Dihydropyridazinones, processes for their preparation and pharmaceutical compositions containing these compounds | BASF Aktiengesellschaft (DE) | 1981-12-23 | — | — | EP | disclosed |
| US-4216099-A | Bridged phenol metal salt/halo carboxylic acid condensate additives for lubricants | THE LUBRIZOL CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| US-4131554-A | Overbased bridged phenol metal salt/halo carboxylic acid condensate additives for lubricants | THE LUBRIZOL CORPORATION (US) | 1978-12-26 | — | — | US | disclosed |
| US-4067698-A | Bridged phenol metal salt-halo carboxylic acid condensate additives for fuels | THE LUBRIZOL CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |