Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 12/20 | 0.54 |
| ▸ | CDC25B | P30305 | 10/20 | 0.54 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034589 | 1.00 | CDC25A (0.54) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL29398347 | 0.87 | CDC25A (0.51) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL29410405 | 0.87 | CDC25A (0.51) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL332666 | 0.87 | CDC25A (0.51) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL29527487 | 0.87 | CDC25A (0.51) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL14116745 | 0.81 | CDC25A (0.51) | CDC25ACDC25BEBP | |
| SCHEMBL29364678 | 0.76 | CDC25A (0.50) | CDC25ACDC25BEBP | |
| SCHEMBL27506460 | 0.75 | CYP2D6 (0.61) | CDC25ACDC25BNPC1L1MEN1USP2 | |
| SCHEMBL9766753 | 0.74 | HMGCR (0.49) | CDC25ACDC25BEBPNPC1L1MEN1 | |
| SCHEMBL9766747 | 0.74 | HMGCR (0.49) | CDC25ACDC25BEBPNPC1L1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080206161-A1 | QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF | FOAMIX PHARMACEUTICALS LTD. (IL) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206161-A1 | QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF | NR5A1, CYP17A1, LIPA | CDC25A 674/4885CDC25B 1342/4885EBP 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.