SCHEMBL14116745

SCHEMBL14116745

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nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CDC25A P30304 12/20 0.51
▸ CDC25B P30305 11/20 0.51
▸ EBP Q15125 4/20 0.41
▸ ACLY P53396 2/20 0.41
▸ ACACA Q13085 2/20 0.41
▸ HSD11B1 P28845 1/20 0.36
▸ HSD11B2 P80365 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1050397 0.85 ACLY (0.48) CDC25ACDC25BEBPACLYACACA
SCHEMBL300737 0.85 ACLY (0.48) CDC25ACDC25BEBPACLYACACA
SCHEMBL14116734 0.81 CDC25A (0.54) CDC25ACDC25BEBP
SCHEMBL14034589 0.81 CDC25A (0.54) CDC25ACDC25BEBP
SCHEMBL29934951 0.81 CDC25A (0.59) CDC25ACDC25BEBPACLYACACA
SCHEMBL2450675 0.80 CDC25A (0.46) CDC25ACDC25BEBPACLYACACA
SCHEMBL2450676 0.80 CDC25A (0.46) CDC25ACDC25BEBPACLYACACA
SCHEMBL2453402 0.76 CDC25A (0.40) CDC25ACDC25BEBPHSD11B1
SCHEMBL2453399 0.76 CDC25A (0.40) CDC25ACDC25BEBPHSD11B1
SCHEMBL3285804 0.73 ACLY (0.61) EBPACLYACACAHSD11B1HSD11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF FOAMIX PHARMACEUTICALS LTD. (IL) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080206161-A1 QUIESCENT FOAMABLE COMPOSITIONS, STEROIDS, KITS AND USES THEREOF NR5A1, CYP17A1, LIPA CDC25A 674/4885CDC25B 1342/4885EBP 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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