SCHEMBL14117969

SCHEMBL14117969

CN[C@@H](CCCCNC(=O)CCOCCOCCOCCOCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.67
▸ FOLH1 Q04609 8/20 0.51
▸ NOD1 Q9Y239 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14117977 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL14118106 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL15579829 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL13146811 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL13146839 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL14117968 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL13146823 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL14117971 1.00 GLP1R (0.67) GLP1RFOLH1NOD1
SCHEMBL13146853 0.97 GLP1R (0.68) GLP1RFOLH1NOD1
SCHEMBL13146867 0.97 GLP1R (0.68) GLP1RFOLH1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171695-A1 Acylated with polyethylene glycol, polypropylene glycol or polybutylene glycol in combination with a fatty diacid; improved bioavailability, first pass effect, solubility at physiological pH values and prolonged pharmacokinetics NOVO NORDISK A/S (DK) 2008-07-17 — — US disclosed
US-20080171695-A1 Acylated with polyethylene glycol, polypropylene glycol or polybutylene glycol in combination with a fatty diacid; improved bioavailability, first pass effect, solubility at physiological pH values and prolonged pharmacokinetics NOVO NORDISK A/S (DK) 2008-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171695-A1 Acylated with polyethylene glycol, polypropylene glycol or polybutylene glycol in combination with a fatty diacid; improved bioavailability, first pass effect, solubility at physiological pH values and prolonged pharmacokinetics IAPP, FABP4, INSR GLP1R 134/4885FOLH1 2002/4885NOD1 1922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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