Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249193 | 1.00 | DRD2 (0.47) | DRD2DRD3CYP3A4MAOAMAOB | |
| SCHEMBL29364314 | 1.00 | DRD2 (0.47) | DRD2DRD3CYP3A4MAOAMAOB | |
| SCHEMBL1249191 | 1.00 | DRD2 (0.47) | DRD2DRD3CYP3A4MAOAMAOB | |
| SCHEMBL12891390 | 0.84 | MAPT (0.47) | DRD2DRD3CYP3A4MAOAMAOB | |
| SCHEMBL232991 | 0.84 | CYP3A4 (0.68) | CYP3A4MAOAMAOBMAPTMAPK1 | |
| SCHEMBL12810063 | 0.80 | MAPT (0.70) | DRD2DRD3CYP3A4MAOAMAOB | |
| SCHEMBL13825739 | 0.78 | DRD2 (0.53) | DRD2DRD3CYP3A4LTB4RLTB4R2 | |
| SCHEMBL8228508 | 0.78 | DRD2 (0.53) | DRD2DRD3CYP3A4LTB4RLTB4R2 | |
| SCHEMBL8231800 | 0.78 | DRD2 (0.53) | DRD2DRD3CYP3A4LTB4RLTB4R2 | |
| SCHEMBL8232785 | 0.78 | DRD2 (0.53) | DRD2DRD3CYP3A4LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765420-B2 | Method for preparing pterocarpan | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-01 | — | — | US | disclosed |
| US-8765420-B2 | Method for preparing pterocarpan | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-01 | — | — | US | disclosed |
| US-8765420-B2 | Method for preparing pterocarpan | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-01 | — | — | US | disclosed |
| US-8633203-B2 | Use of pterocarpans as active anti-cellulite ingredients | SYMRISE AG (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20130130332-A1 | NOVEL METHOD FOR PREPARING PTEROCARPAN | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-05-23 | — | — | US | disclosed |
| US-20130130332-A1 | NOVEL METHOD FOR PREPARING PTEROCARPAN | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-05-23 | — | — | US | disclosed |
| US-20130130332-A1 | NOVEL METHOD FOR PREPARING PTEROCARPAN | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-05-23 | — | — | US | disclosed |
| EP-2295031-A2 | Use of pterocarpans as anti-cellulite agents | Symrise AG (DE) | 2011-03-16 | — | — | EP | disclosed |