Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 14/20 | 0.51 |
| ▸ | NPY1R | P25929 | 8/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.51 |
| ▸ | NPY2R | P49146 | 5/20 | 0.51 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.47 |
| ▸ | IL1RN | P18510 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123197 | 1.00 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL14123099 | 0.93 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL14123101 | 0.93 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL15579617 | 0.91 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL15579528 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL14122910 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RACE | |
| SCHEMBL14123199 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL15579531 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RP2RY1 | |
| SCHEMBL14123191 | 0.90 | NPY4R (0.52) | NPY4RNPY1RNPY5RNPY2RACE | |
| SCHEMBL14123084 | 0.90 | CAPN1 (0.57) | NPY4RNPY1RNPY5RNPY2RACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673904-B2 | Epoxide inhibitors of cysteine proteases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-18 | — | — | US | disclosed |
| US-8673904-B2 | Epoxide inhibitors of cysteine proteases | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-03-18 | — | — | US | disclosed |
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176841-A1 | EPOXIDE INHIBITORS OF CYSTEINE PROTEASES | SERPINB1, EPHX1, EPX | NPY4R 4838/4885NPY1R 4739/4885NPY5R 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.