SCHEMBL14124752

SCHEMBL14124752

O=C(c1ccccc1)c1ccc(Cc2ccc(C(=O)c3ccccc3C(=O)O)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.74
CDC25B P30305 2/20 0.65
ATM Q13315 1/20 0.65
NR4A1 P22736 1/20 0.62
CDC25A P30304 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TSHR P16473 1/20 0.59
KDM4E B2RXH2 1/20 0.58
SRD5A2 P31213 3/20 0.56
ALDH1A1 P00352 3/20 0.53
POLB P06746 1/20 0.53
ALOX15 P16050 1/20 0.52
PLA2G10 O15496 1/20 0.52
PLA2G2A P14555 1/20 0.52
LMNA P02545 1/20 0.52
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA9 Q16790 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124724 0.94 AKR1C3 (0.70) AKR1C3CDC25BATMNR4A1CDC25A
2-Benzoylbenzoic Acid SCHEMBL29024593 0.88 AKR1C3 (0.95) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL8094666 0.88 ALDH1A1 (0.67) AKR1C3ATMSRD5A2ALDH1A1PLA2G10
SCHEMBL4004691 0.86 LMNA (0.67) ATMSRD5A2ALDH1A1PLA2G10PLA2G2A
2-Benzoylbenzoic Acid SCHEMBL30296847 0.86 AKR1C3 (1.00) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL27524893 0.86 AKR1C3 (0.91) AKR1C3CDC25BATMNR4A1CDC25A
2-Benzoylbenzoic Acid SCHEMBL76332 0.86 AKR1C3 (1.00) AKR1C3CDC25BATMNR4A1CDC25A
SCHEMBL14124723 0.85 AKR1C3 (0.68) AKR1C3CDC25BATMNR4A1CDC25A
2-Benzoylbenzoic Acid SCHEMBL3791911 0.84 AKR1C3 (0.95) AKR1C3CDC25BATMNR4A1CDC25A
2-Benzoylbenzoic Acid SCHEMBL9317427 0.84 AKR1C3 (0.95) AKR1C3CDC25BATMNR4A1CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7396488-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2008-07-08 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed
US-20070085057-A1 LIGHT EMITTING DEVICE AND FLUORESCENT MATERIAL MITSUBISHI CHEMICAL CORPORATION (JP) 2007-04-19 US disclosed