Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.69 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 2/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14125660 | 1.00 | BHMT (0.69) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL14125658 | 1.00 | BHMT (0.69) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1038668 | 0.85 | BHMT (0.92) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL6664390 | 0.85 | BHMT (0.71) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1038667 | 0.85 | BHMT (0.92) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL9056803 | 0.85 | BHMT (0.92) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1031686 | 0.84 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL21851894 | 0.84 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1031684 | 0.84 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL27791649 | 0.84 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180050004-A1 | USES OF AND METHODS OF TREATMENT WITH CYSTATHIONINE | UNIV COLORADO REGENTS (US) | 2018-02-22 | — | — | US | claimed |
| US-20200352889-A1 | CYSTATHIONINE COMPOSITIONS AND METHODS OF TREATMENT FOR HEALTH CONDITIONS | MCMASTER UNIVERSITY (CA) | 2020-11-12 | — | — | US | disclosed |
| US-20180050004-A1 | USES OF AND METHODS OF TREATMENT WITH CYSTATHIONINE | UNIV COLORADO REGENTS (US) | 2018-02-22 | — | — | US | disclosed |
| US-20140163104-A1 | USES OF AND METHODS OF TREATMENT WITH CYSTATHIONINE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2014-06-12 | — | — | US | disclosed |
| WO-2012167092-A2 | USES OF AND METHODS OF TREATMENT WITH CYSTATHIONINE | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012167021-A2 | HYPERFORIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2012-12-06 | — | — | WO | disclosed |