Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18736193 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL18401230 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL14129337 | 0.82 | ALDH1A1 (0.56) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL649272 | 0.75 | IDO1 (0.44) | — | |
| SCHEMBL14516988 | 0.74 | APP (0.49) | ALDH1A1HPGDMEN1KMT2ATHRB | |
| SCHEMBL14129338 | 0.74 | GLA (0.59) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL14129336 | 0.73 | SMN1; SMN2 (0.54) | ALDH1A1HPGDLMNAMAPTMEN1 | |
| SCHEMBL13814427 | 0.73 | TDP1 (0.45) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL12134040 | 0.72 | ACACB (0.39) | LMNAL3MBTL1 | |
| SCHEMBL11979782 | 0.72 | TAAR1 (0.50) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396828-B2 | PI-3 kinase inhibitor prodrugs | SEMAFORE PHARMACEUTICALS, INC. (US) | 2008-07-08 | — | — | US | disclosed |