SCHEMBL14129679

SCHEMBL14129679

Cc1ccc(C=Nc2ccc(C)cn2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
ALDH1A1 P00352 6/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TP53 P04637 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
TSHR P16473 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ADRA2A P08913 2/20 0.47
ADRA2B P18089 2/20 0.47
ADRA2C P18825 2/20 0.47
PLAU P00749 1/20 0.47
USP2 O75604 2/20 0.46
GAA P10253 2/20 0.46
PTGS2 P35354 2/20 0.40
CCR1 P32246 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14129667 0.86 KDM4E (0.46) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL14728791 0.86 PKM (0.54) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL14129686 0.85 KDM4E (0.48) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL14129763 0.78 NPC1 (0.50) KDM4EALDH1A1HPGDMEN1KMT2A
SCHEMBL28089833 0.78 KDM4E (0.55) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL14129004 0.75 KDM4E (0.52) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL1356192 0.73 ADRA2A (0.47) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL1356191 0.73 ADRA2A (0.47) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL11706620 0.73
Hydrochloric Acid SCHEMBL11707885 0.71 ADRA2A (0.57) KDM4EALDH1A1MAPTHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360387-B A kind of method preparing compound zolpidem 江苏豪森药业集团有限公司 2016-12-14 CN disclosed
US-7393598-B2 Light emitting molecules and organic light emitting devices including light emitting molecules HCF PARTNERS, L.P. (US) 2008-07-01 US disclosed