SCHEMBL14129688

SCHEMBL14129688

Cc1ccc(C=Cc2ccc(C)nc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.50
RELA Q04206 1/20 0.47
PTGS1 P23219 2/20 0.44
PTGS2 P35354 2/20 0.44
ALOX5 P09917 1/20 0.44
FGF23 Q9GZV9 3/20 0.42
CA1 P00915 1/20 0.42
KDM4E B2RXH2 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
TUBB4A P04350 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13053141 0.85 CYP11B1 (0.55) NFE2L2RELAKDM4ECYP1A2CYP2C9
SCHEMBL14129562 0.84 MAPT (0.41) NFE2L2KDM4ECYP1A2CYP2C9NPC1
SCHEMBL5652710 0.83 KDM4E (0.53) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL935872 0.83 PADI4 (0.36) ALOX5KDM4ECYP1A2POLBCYP2C19
SCHEMBL935871 0.83 PADI4 (0.36) ALOX5KDM4ECYP1A2POLBCYP2C19
SCHEMBL13320184 0.83 PADI4 (0.36) ALOX5KDM4ECYP1A2POLBCYP2C19
SCHEMBL5652716 0.83 KDM4E (0.53) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL13236614 0.83 CCR1 (0.56) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL14129689 0.82 TUBB4A (0.33) NFE2L2PTGS1PTGS2ALOX5KDM4E
SCHEMBL9000469 0.81 GRM4 (0.39) PTGS1PTGS2ALOX5FGF23CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7393598-B2 Light emitting molecules and organic light emitting devices including light emitting molecules HCF PARTNERS, L.P. (US) 2008-07-01 US disclosed