SCHEMBL13053141

SCHEMBL13053141

Cc1ccc(C=Cc2ccccc2)cn1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.55
CYP11B2 P19099 1/20 0.55
GRM5 P41594 2/20 0.53
RELA Q04206 2/20 0.50
ALDH1A1 P00352 4/20 0.48
GRM4 Q14833 3/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP3A4 P08684 2/20 0.48
THPO P40225 2/20 0.48
HIF1A Q16665 2/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14129688 0.85 NFE2L2 (0.50) RELAKDM4EHPGDCYP3A4NPC1
SCHEMBL935872 0.81 PADI4 (0.36) CYP11B1CYP11B2GRM5KDM4EHDAC6
SCHEMBL935871 0.81 PADI4 (0.36) CYP11B1CYP11B2GRM5KDM4EHDAC6
SCHEMBL13320184 0.81 PADI4 (0.36) CYP11B1CYP11B2GRM5KDM4EHDAC6
Styrene SCHEMBL10707688 0.80 ALDH1A1 (0.54) CYP11B1CYP11B2GRM5RELAALDH1A1
SCHEMBL9000469 0.79 GRM4 (0.39) GRM5ALDH1A1GRM4NPC1RAB9A
SCHEMBL16502107 0.79 APP (0.53)
SCHEMBL17132081 0.79 CYP1A2 (0.46) ALDH1A1KDM4EHPGDMEN1KMT2A
SCHEMBL4580523 0.78 MEN1 (0.64) CYP11B1CYP11B2GRM5RELAALDH1A1
SCHEMBL4580522 0.78 MEN1 (0.64) CYP11B1CYP11B2GRM5RELAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838131-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2010-11-23 US disclosed
US-20100044638-A1 1,3,5-Tri((2-(methyl-)benzimidazol-1-yl)-)benzene; OLED'shaving a light emission maximum wavelength of 500 nm or less wherein the minimum excitation triplet energy level of the host material is higher than the minimum excitation triplet energy level of the light emitting material FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
US-7632579-B2 Light emitting element and azole compound FUJIFILM CORPORATION (JP) 2009-12-15 US disclosed