Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14140402 | 0.93 | HRH3 (0.54) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL14129564 | 0.89 | MAPT (0.48) | DRD4AKR1C3HRH3KDM4E | |
| SCHEMBL6884731 | 0.88 | HRH3 (0.46) | AKR1C3HRH3 | |
| SCHEMBL5056216 | 0.84 | HRH3 (0.48) | TMEM97SIGMAR1ADRA2AADRA2BADRA2C | |
| SCHEMBL14129697 | 0.84 | NPC1 (0.50) | DRD4LMNAAKR1C3HRH3KDM4E | |
| SCHEMBL14140523 | 0.81 | HRH3 (0.56) | TMEM97SIGMAR1DRD4AKR1C3HRH3 | |
| SCHEMBL578590 | 0.81 | HRH3 (0.65) | LMNAHRH3ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL23860313 | 0.79 | HRH3 (0.62) | LMNAHRH3ALDH1A1HPGD | |
| SCHEMBL12494973 | 0.79 | AKR1C3 (0.66) | LMNAAKR1C3KDM4EALDH1A1HPGD | |
| SCHEMBL948372 | 0.78 | SIGMAR1 (0.68) | SIGMAR1DRD4LMNAHRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7393598-B2 | Light emitting molecules and organic light emitting devices including light emitting molecules | HCF PARTNERS, L.P. (US) | 2008-07-01 | — | — | US | disclosed |