Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NCF1 | P14598 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2A13 | Q16696 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.57 |
| ▸ | MC4R | P32245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18065638 | 1.00 | SIGMAR1 (0.68) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL896379 | 1.00 | SIGMAR1 (0.68) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL102338 | 0.98 | SIGMAR1 (0.71) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL6200777 | 0.98 | SIGMAR1 (0.71) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| Water SCHEMBL1702298 | 0.96 | SIGMAR1 (0.68) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| Hydrochloric Acid SCHEMBL6261135 | 0.96 | SIGMAR1 (0.68) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL28158277 | 0.96 | SIGMAR1 (0.68) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL6384833 | 0.94 | HRH3 (0.61) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL18309364 | 0.94 | HRH3 (0.61) | SIGMAR1HRH3ALDH1A1HTTKDM4E | |
| SCHEMBL24200050 | 0.93 | HRH3 (0.62) | SIGMAR1HRH3ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9550704-B2 | Method for synthesizing radiopharmaceuticals using a cartridge | FUTURECHEM CO., LTD. (KR) | 2017-01-24 | — | — | US | claimed |
| US-20150232392-A1 | METHOD FOR SYNTHESIZING RADIOPHARMACEUTICALS USING A CARTRIDGE | FUTURECHEM CO., LTD. (KR) | 2015-08-20 | — | — | US | claimed |
| US-8641903-B2 | Method for the preparation of reactive [18] F fluoride | TRASIS S.A. (BE) | 2014-02-04 | — | — | US | claimed |
| EP-2115177-B1 | METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP | TRASIS S A (BE) | 2011-05-11 | — | — | EP | claimed |
| US-20110006011-A1 | METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP | TRASIS S.A. (BE) | 2011-01-13 | — | — | US | claimed |
| US-20100243972-A1 | METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE | TRASIS S.A. (BE) | 2010-09-30 | — | — | US | claimed |
| WO-2026102309-A1 | SELECTIVE RADIOTRACERS AND METHODS OF USE | LUTROO IMAGING, LLC (US) | 2026-05-15 | — | — | WO | disclosed |
| US-20250352676-A1 | N-Cyclopropyl-1-(4-(4-(Fluoro-18f)Phenyl)Pyrimidin-5-Yl)-N-Methylpiperidine- 4-Carboxamide and Uses in PET Imaging | UNIV EMORY (US) | 2025-11-20 | — | — | US | disclosed |
| WO-2024035925-A2 | N-CYCLOPROPYL-1-(4-(4-(FLUORO-18F)PHENYL)PYRIMIDIN-5-YL)-N-METHYLPIPERIDINE-4-CARBOXAMIDE AND USES IN PET IMAGING | EMORY UNIVERSITY (US) | 2024-02-15 | — | — | WO | disclosed |
| US-20230158178-A1 | Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof | UNIV EMORY (US) | 2023-05-25 | — | — | US | disclosed |
| US-20220306663-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | UNIV EMORY (US) | 2022-09-29 | — | — | US | disclosed |
| US-11384106-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | EMORY UNIVERSITY (US) | 2022-07-12 | — | — | US | disclosed |
| CN-107847617-B | Metal tricarbonyl complexes containing substituted iminodiacetic acid ligands and their use as radiotracers | 爱默蕾大学 | 2021-08-31 | — | — | CN | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | ASHAI KASEI PHARAMA CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-4734376-A | SELECTIVE EXTRACTION AND COLORMETRIC DETERMINATION | THE PRESIDENT & TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1988-03-29 | — | — | US | disclosed |
| US-4659815-A | Chromogenic aza-12-crown-4 ethers and method of using same for the detection of lithium | THE PRESIDENT AND TRUSTEES OF THE MIAMI UNIVERSITY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0079920-B1 | NEW AZA-CROWN-ETHERS AND THEIR USE | BORREGAARD INDUSTRIES LIMITED (NO) | 1986-10-15 | — | — | EP | disclosed |
| EP-0079920-A1 | NEW AZA-CROWN-ETHERS AND THEIR USE. | BORREGAARD IND (NO) | 1983-06-01 | — | — | EP | disclosed |
| WO-1982004253-A1 | NEW AZA-CROWN-ETHERS AND THEIR USE | DALE JOHANNES | 1982-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232392-A1 | METHOD FOR SYNTHESIZING RADIOPHARMACEUTICALS USING A CARTRIDGE | ADCYAP1R1, PAICS, SSTR5 | SIGMAR1 1612/4885HRH3 1134/4885ALDH1A1 2900/4885 |
| US-20220306663-A1 | Metal Tricarbonyl Complexes Comprising Substituted Iminodiactic Acid Ligands and Uses as Radioisotope Tracers | SLC16A8, S100A8, FGF23 | SIGMAR1 2627/4885HRH3 1668/4885ALDH1A1 1595/4885 |
| US-20230158178-A1 | Radionuclide Tracers of 1-Amino-3,4-Difluorocyclopentane-1-Carboxylic Acid, Derivatives, and Uses Thereof | AFF1, METTL3, VHL | SIGMAR1 1249/4885HRH3 2475/4885ALDH1A1 243/4885 |
| US-11384106-B2 | Metal tricarbonyl complexes comprising substituted iminodiactic acid ligands and uses as radioisotope tracers | SLC16A8, S100A8, FGF23 | SIGMAR1 2627/4885HRH3 1668/4885ALDH1A1 1595/4885 |
| US-20070190041-A1 | Novel benzothiazepine and bensothiepine compounds | SLC10A1, GOT1, CES1 | SIGMAR1 161/4885HRH3 404/4885ALDH1A1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.